Zona pellucida birefringence score and meiotic spindle visualization in relation to embryo development and ICSI outcomes

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Zona pellucida birefringence score and meiotic spindle visualization in relation to embryo development and ICSI outcomes.

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Background: The meiotic spindle plays an important role in the oocyte during chromosome alignment and separation at meiosis. The zona pellucid (ZP) is a dynamic matrix composed of filaments with the properties that might reflect the history of oocyte cytoplasmic maturation. Since, spindle and ZP in living oocytes are highly birefringent, their structures can be viewed noninvasively by using a P...

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Background Polycystic ovarian syndrome (PCOs) is one of the most common causes of infertility in women of reproductive age. Currently, one of the best therapeutic options for PCOs patients is ICSI. Moreover, IVM can be a useful technique for women with PCOs who are at the risk of ovarian hyperstimulation syndrome (OHSS). On the other hand, the oocyte quality can be a determining factor for outc...

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ژورنال

عنوان ژورنال: Reproductive BioMedicine Online

سال: 2009

ISSN: 1472-6483

DOI: 10.1016/s1472-6483(10)60014-4